HGH is safe and is best when used for extended periods of time. A typical cycle lasts 9 months to 1 year. A rejuvenation dose of 1IU per day can be sustained indefinately, meaning you can stay on it as long as you like. Higher doses like 2IU or 4IU a day are best to run for 9 months to a year and then take a break. Call us and have your HGH questions answered today!